Aerosolisation During Respiratory Procedures

Guy's and St Thomas' NHS Foundation Trust

Status: Unknown

Conditions: Healthy; Lung Infection; Respiratory Tract Infections; Droplet Spread

Treatments: Other: Not an interventional study

Study type: Observational

Funder types: Other

Identifiers

NCT04741217

288629

Details and patient eligibility

About

Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-80 years
• Healthy subjects with no active medical conditions or previous pneumothorax
• Cognitively and linguistically able to follow instructions given in English and provide informed consent

Exclusion criteria

• Significant respiratory, cardiac or neurological conditions or previous pneumothorax
• Smoking history greater than 10 pack years
• Acute illness at the time of assessment
• Allergies to latex, metals or local anaesthetic agents