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Aetiologies and Prognosis of Small Bowel Obstruction in Virgin Abdomen

N

Nanjing Medical University

Status

Completed

Conditions

Small Bowel Obstruction
Small Bowel Obstruction Adhesion

Study type

Observational

Funder types

Other

Identifiers

NCT07150390
2023-SR-340

Details and patient eligibility

About

Small bowel obstruction (SBO) is a surgical emergency in which the passage of intestinal contents is prevented due to mechanical obstruction of small intestine. It accounts for almost 50% of all emergency laparotomies with significant in-hospital morbidity and costs. SBO has known to occur in patients who had no prior abdominal surgery, referring to as a virgin abdomen (VA). Nowadays, non-operative management comprising of bowel decompression, water-soluble contrast agents, and fluid resuscitation have been found safe and efficacious in 70% of SBOs caused by adhesions (ASBO). However, based on the assumption that SBO in the virgin abdomen (SBO-VA) is usually caused by other aetiologies than adhesions, such as malignancy and hernias, many authors suggest that surgical exploration is still mandatory. Besides, recent studies do show high incidence of adhesions also in patients with SBO-VA. This observation signifies that guideline on the management of ASBO might also apply to the majority of patients with SBO-VA. Hence, the aim of our retrospectively study is to shed light on the aetiologies of SBO-VA. We believe treatment strategy needs to be based on the underlying reasons of obstructions and conditions of the patients and evaluate their prognosis accordingly.

Enrollment

312 patients

Sex

All

Ages

14+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Only patients without prior abdominal operations and with CT or surgical exploration confirmation of the diagnosis of SBO were included.

Exclusion criteria

  • Patients with age less than 14 years were excluded in this study.

Trial design

312 participants in 1 patient group

SBO-VA
Description:
small intestinal obstruction patients without a history of abdominal surgery (virgin abdomen)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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