AFIX to Improve HPV Vaccination

University of North Carolina (UNC)

Status: Completed

Conditions: Papillomavirus Vaccines; Adolescent Health Services

Treatments: Other: AFIX in-person consultation; Other: AFIX webinar consultation

Study type: Interventional

Funder types: Other

Identifiers

NCT02370459

13-3599

71272 (Other Grant/Funding Number)

Details and patient eligibility

About

The University of North Carolina will test the effectiveness of the Centers for Disease Control and Prevention's AFIX model for increasing HPV vaccination coverage among adolescents. AFIX (Assessment, Feedback, Incentives and eXchange) consists of brief quality improvement consultations that immunization specialists from state health departments deliver to vaccine providers in primary care settings. Using immunization registry data, the specialist evaluates the clinic's vaccination coverage and delivers education on best practices to improve coverage. We will compare changes in HPV vaccination coverage before and after consultations for high-volume pediatric and family medicine clinics across three study conditions: traditional consultations (in-person group), virtual consultations (webinar group), or no consultations (control group). In each participating state, 30 clinics will be randomly assigned to each study arm, for a total of 90 clinics per state, or 270 clinics overall. The primary objective of this study is to compare the change in coverage for HPV vaccine initiation among 11-12 year old patients, from baseline to 6-month follow-up. Secondarily, we will compare the change in coverage for other vaccines and age groups.

Enrollment: 223 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Pediatric or family medicine clinics or practices in WA, IL, or MI with

• at least 500 active records for patients, ages 11-17, in their states' immunization information systems.

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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223 participants in 3 patient groups

control

No Intervention group

Description:

This arm includes 30 high-volume primary care clinics in each of three states (Washington, Illinois, Michigan) for a total of 90 clinics. Clinics randomly assigned to this arm will receive no AFIX consultation.

AFIX in-person consultation

Experimental group

Description:

This arm includes 30 high-volume primary care clinics in each of three states (Washington, Illinois, Michigan) for a total of 90 clinics. Clinics randomly assigned to this arm will receive an in-person AFIX consultation. Consultations will be delivered by state health department staff.

Treatment:

Other: AFIX in-person consultation

AFIX webinar consultation

Experimental group

Description:

This arm includes 30 high-volume primary care clinics in each of three states (Washington, Illinois, Michigan) for a total of 90. Clinics randomly assigned to this arm will receive an AFIX consultation via interactive webinar. Consultations will be delivered by state health department staff.

Treatment:

Other: AFIX webinar consultation