Agreement Among Expert Radiologists in Diagnosing Primary Liver Tumors by Magnetic Resonance Imaging (MRI) (MRevaluation)

University of Zurich (UZH)

Status: Completed

Conditions: Neoplasms

Treatments: Other: Histopathology diagnosis of resected liver specimen; Other: Non-invasive Magnetic Resonance Imaging (MRI); Procedure: Liver resection

Study type: Observational

Funder types: Other

Identifiers

NCT01234701

MRI_Liver_Tumours_Evlauation

Details and patient eligibility

About

The purpose of this multicenter study is to evaluate the agreement among expert radiologists in interpreting magnetic resonance images (MRI) assessing common primary liver tumours in non-cirrhotic patients.

Full description

Magnetic Resonance Imaging (MRI) is currently the method of choice for non-invasive diagnosis of primary liver tumors. However, differentiation of hepatocellular carcinoma (HCC) from adenoma and focal nodular hyperplasia (FNH) remains challenging, particularly in non-cirrhotic patients.

Enrollment: 108 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histopathological diagnosis of Hepatocellular Cancer (HCC), Adenoma and/or Focular nodular hyperplasia (FNH).
• Patients that received a pre-operative Magnetic Resonance Imaging (MRI).
• Patients that underwent liver resection with an intention to cure.
• Patient over 18 years of age

Exclusion criteria

• Other histopathological diagnosis such as cysts and hemangiomas.
• Patient age less than 18 years of age.

Trial design

108 participants in 1 patient group

Primary liver tumors, non-cirrhotic

Description:

This single Cohort/Group will include all consecutive patients that received pre-operative Magnetic Resonance Imaging (MRI) and underwent resection for primary liver tumors.

Treatment:

Procedure: Liver resection

Other: Non-invasive Magnetic Resonance Imaging (MRI)

Other: Histopathology diagnosis of resected liver specimen