Agreement Between Arterial, Central Venous, and Peripheral Venous Lactate in the Intensive Care Unit
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Details and patient eligibility
About
The main objective of this study is to examine the agreement between arterial, central venous, and peripheral venous lactate values in a population of medical Intensive Care Unit (ICU) patients.
Full description
This study is a single-center, prospective trial to assess the agreement between arterial, central venous, and peripheral venous lactate measurements. When an arterial lactate is deemed to be necessary as part of ICU management, a central venous and peripheral venous sample will also obtained within 5 minutes. All of the samples will be analyzed using the same analyzer as quickly as possible. A maximum of 10 paired arterial and venous lactate samples will be obtained per patient to prevent a single patient from dominating the data set. Additional data collected on a standardized data collection form will include primary diagnosis, intubation status, use of inotropic agents, hypotension (defined as a systolic blood pressure < 90 mm Hg), ICU length of stay and mortality. The Bland-Altman method will be used to assess agreement between arterial (A), central venous(CV), and peripheral venous (PV) lactate measurements. Approximately 50 patients will be enrolled in this study.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Adult patients 18 years or older
- Admitted to the Intensive Care Unit (ICU)
- Determined by their treating clinicians to require both a central venous line and arterial line
Exclusion criteria
- None
Trial design
Primary purpose
Allocation
Interventional model
Masking
50 participants in 1 patient group
Trial contacts and locations
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Central trial contact
Richard Treger, MD
Data sourced from clinicaltrials.gov
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