Agreement Between Oral and Cervical Human Papillomavirus Infection in a French Cohort (PAPILLOR)

Institut de Cancérologie de Lorraine

Status: Completed

Conditions: Human Papillomavirus-Related Cervical Carcinoma

Treatments: Other: Agreement between oral and cervical HPV infection

Study type: Interventional

Funder types: Other

Identifiers

NCT02774538

2015-A00594-45

Details and patient eligibility

About

Human papillomaviruses (HPVs) are the most common of sexually transmitted viral agents and they are associated with genital and oral diseases.

Agreement between cervical and oral HPV infection has been described from a small group of patient. Our study, performed on a greater number of patients, will provide a good estimation of this link, between cervical and oral infection, in a French population of women with a primary cervical HPV infection.

Enrollment: 165 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologic proven of cervical intraepithelial neoplasia or carcinoma in situ (CIS) or invasive cervical cancer or a Pap smear on which at least one HPV has been detected
• Patients not vaccinated against HPV
• Age >18 years
• EOCG performance status ≤ 3
• Patient must be affiliated to a social security system
• Ability to provide written informed consent patient's legal capacity to consent to study participation and to understand and comply with the requirements of the study

Exclusion criteria

• Patients vaccinated against HPV
• Pregnant woman over 10 weeks
• Patient who underwent head and neck radiotherapy dating less than one year
• Patients deprived of liberty or under supervision

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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165 participants in 1 patient group

Experimental arm

Other group

Treatment:

Other: Agreement between oral and cervical HPV infection