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This study aims to develop and validate an artificial intelligence (AI) system that can predict whether lymph node metastasis has occurred in patients with gastric cancer before surgery. Using preoperative imaging and pathology data, the AI models will not only predict if metastasis is present but also identify which specific lymph node stations or individual lymph nodes are involved. All lymph nodes will be carefully removed during surgery and examined one by one with detailed pathological methods to ensure accurate diagnosis. The goal is to improve the accuracy of lymph node assessment and assist doctors in making better treatment decisions.
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Inclusion criteria
Histologically confirmed gastric adenocarcinoma
Scheduled for curative-intent gastrectomy with lymphadenectomy
Completed preoperative imaging with contrast-enhanced CT or MRI
Available preoperative biopsy pathology report
Able and willing to provide written informed consent
Exclusion criteria
Prior chemotherapy, radiotherapy, or major abdominal surgery
Severe comorbidities contraindicating surgery
Incomplete or poor-quality preoperative imaging or pathology data
Pregnancy or lactation
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Data sourced from clinicaltrials.gov
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