AI-Driven MRF Type 2 Diabetes Integrating DHT IF and Resistance Training to OM and Functional Outcomes

Superior University

Status: Active, not recruiting

Conditions: Type 2 Diabetes Mellitus 1

Treatments: Diagnostic Test: Standard Diabetes Care; Combination Product: AI-Guided Multimodal Rehabilitation Program

Study type: Interventional

Funder types: Other

Identifiers

NCT07336459

PhDRSW/Batch-Fall23/2228

Details and patient eligibility

About

This randomized controlled trial aims to evaluate the effectiveness of an AI-driven multimodal rehabilitation framework combining digital health technologies, intermittent fasting, and resistance training in individuals with Type 2 Diabetes Mellitus (T2DM). The study will integrate mobile-based AI monitoring for glucose trends, physical activity tracking, and dietary adherence reminders, thereby improving patient engagement and self-management.

Full description

Participants will be randomized into two groups: the intervention group receiving AI-guided resistance training alongside intermittent fasting, and the control group receiving standard diabetes care. Outcomes will include changes in HbA1c, insulin sensitivity (HOMA-IR), muscle strength, functional mobility, and quality of life. The study will also assess adherence, feasibility, and cost-effectiveness. By utilizing AI-enabled technology and lifestyle-based interventions, this study addresses the gap between clinical management and sustainable self-care in T2DM. The framework is designed to be low-cost, scalable, and adaptable, making it suitable for resource-limited healthcare systems.

Enrollment: 60 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with Type 2 Diabetes (≥1 year)
• HbA1c between 6.5% and 9.0%
• Sedentary or low physical activity levels
• BMI: 25-35 kg/m²
• Able to perform mild-to-moderate exercise

Exclusion criteria

• any other disability
• not willing

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

AI-Guided Multimodal Rehabilitation Program

Experimental group

Treatment:

Combination Product: AI-Guided Multimodal Rehabilitation Program

Standard Diabetes Care

Active Comparator group

Treatment:

Diagnostic Test: Standard Diabetes Care