AI-Driven Prediction of Hospital-Acquired Infections With EHR

Wenzhou Medical University

Status: Enrolling

Conditions: Hospital-acquired Infections

Treatments: Diagnostic Test: AI-Based Diagnostic and Prognostic Model

Study type: Observational

Funder types: Other

Identifiers

NCT06791382

Hospital-Acquired Infections

Details and patient eligibility

About

This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying and diagnosing infection, leveraging multimodal health data.

Full description

Hospital-acquired infections (HAIs) are a significant cause of morbidity and mortality in healthcare settings. Early identification and prevention of HAIs are crucial for improving patient outcomes, reducing healthcare costs, and preventing the spread of infections. In clinical practice, healthcare providers often need to integrate a wide range of patient data, including medical history, laboratory test results, medication usage, surgical procedures, and clinical observations, to assess infection risks and prevent HAIs. As infection control and precision medicine become increasingly important, the challenge remains to predict and prevent infections, especially in patients with subtle or asymptomatic risk factors. Recent advancements in artificial intelligence and data analysis techniques have shown great promise in improving the accuracy and efficiency of infection prediction and prevention. This study aims to develop an AI-assisted decision-making system by integrating multimodal data from electronic health records, lab results, clinical observations, and patient demographics. The objective is to enhance the early identification of patients at risk for HAIs, streamline clinical workflows, and optimize infection control measures. Ultimately, this system seeks to reduce the incidence of hospital-acquired infections, improve patient safety, and enhance overall healthcare quality.

Enrollment: 1,000,000 estimated patients

Sex: All

Ages: Under 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with complete and accessible EHR data, including medical history, laboratory test results, treatment regimens, clinical observations, and infection history.
2. Patients who have been admitted to the participating hospital or healthcare facility during the study period.
3. All participants must provide informed consent to use their health data for research purposes.

Exclusion criteria

1. Patients with incomplete or missing critical EHR data, such as lab results, medical history, or treatment details, which are necessary for infection prediction.
2. Patients who have severe cognitive disorders, dementia, or conditions that prevent them from providing informed consent or participating in the study.
3. Patients who have not been admitted to the hospital during the study period or who are receiving outpatient care only.
4. Patients with terminal conditions where infection prediction may not be applicable to the clinical goals of the study.

Trial design

1,000,000 participants in 2 patient groups

Hospital-Acquired Infection Cohort

Description:

This group consists of patients who have developed a hospital-acquired infection (HAI) during their hospital stay. Participants in this cohort will be used to evaluate the effectiveness of the AI-assisted predictive model in identifying the risk factors leading to hospital-acquired infections. The model will be assessed based on the accuracy of predicting infection risks in hospitalized patients. No specific interventions will be provided as part of this cohort beyond the existing hospital infection control practices.

Treatment:

Diagnostic Test: AI-Based Diagnostic and Prognostic Model

Healthy Cohort (No HAI)

Description:

This group consists of patients who have not developed any hospital-acquired infections during their hospital stay. Participants in this cohort will serve as the control group for comparison against the experimental group. The AI-assisted model will be evaluated for its ability to distinguish between patients who are at risk for developing infections and those who remain infection-free during hospitalization. No interventions will be provided as part of this cohort, as they represent patients without infection-related complications.

Treatment:

Diagnostic Test: AI-Based Diagnostic and Prognostic Model