Airway Clearance Technique of Oscillation and Lung Expansion in Bronchiectasis

Shanghai Pulmonary Hospital, Shanghai, China

Status: Enrolling

Conditions: Bronchiectasis Adult

Treatments: Drug: Anti-infective therapy; Behavioral: Postural drainage; Device: Oscillation and Lung Expansion; Drug: Mucolytic

Study type: Interventional

Funder types: Other

Identifiers

NCT06393257

20230901

Details and patient eligibility

About

The goal of this prospective randomized controlled trial is to explore the efficacy and safety of Oscillation and Lung Expansion-a airway clearance technology-in bronchiectasis. Participants will receive Oscillation and Lung Expansion or postural drainage randomly in this study. and the symptom, quality of life scores and amount of expectoration will be compared between the two groups.

Enrollment: 96 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with acute exacerbation of bronchiectasis

Exclusion criteria

• Haemoptysis greater than 50ml
• state of endangerment
• pneumothorax
• Lung surgery history within 6 months
• Severe heart, brain and nervous system diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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96 participants in 2 patient groups

Oscillation and Lung Expansion

Experimental group

Treatment:

Device: Oscillation and Lung Expansion

Drug: Mucolytic

Drug: Anti-infective therapy

postural drainage

Active Comparator group

Treatment:

Drug: Mucolytic

Drug: Anti-infective therapy

Behavioral: Postural drainage