Airway Management During TCI vs RSI Anesthesia Induction

Umeå University

Status: Completed

Conditions: Adverse Effect; Airway Complication of Anesthesia; Anesthesia

Treatments: Procedure: Induction of anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT03723109

2016/361-31 IV

Details and patient eligibility

About

The aims of this observational study is to evaluate and compare feasibility of airway management during standardized TCI and RSI anesthesia induction.

Full description

The aims of this study are to evaluate and compare feasibility of airway management and risk for desaturation during standardized target controlled infusion (TCI) and rapid sequence induction (RSI) of anesthesia. A conventional way to induce anesthesia, i.e. manual injection of anesthetics, may be more accurate and predictable compared to dosing regimes based on complex mathematical algorithms used in TCI-systems. In addition, today many different models are presented and there is no consensus which kind of TCI-algorithm should be used universally. Moreover, dosing algorithms are most complex and challenging in underweight and morbid obesity. There are many publications on this field, but no data of feasibility of airway management can be found. Indeed, RSI induction is traditionally blamed to be risky and not recommended as a first choice.

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• signed informed consent
• BMI < 35 kg/m2
• preoperative assessment accepted by consultant anesthesiologist
• scheduled for breast cancer surgery, endocrinological surgery (thyroid, parathyroid) or minor general abdominal surgery.

Exclusion criteria

• not signed consent
• instable angina pectoris
• severe bronchial asthma
• severe chronic obstructive pulmonary disease
• dementia
• severe heart valve disease
• severe renal failure
• body mass index > 35 kg/m2