Alcohol Cessation Intervention in an Acute Surgical Setting

Bispebjerg Hospital

Status

Completed

Conditions

Postoperative Complications

Infection

Acute Fracture Surgery

Ankle Injuries

Alcohol Cessation Intervention

Treatments

Other: GSP-A

Study type

Interventional

Funder types

Other

Identifiers

NCT00986791

Scand-Ankle

Details and patient eligibility

About

Hazardous alcohol intake is an independent risk factor for postoperative complications after major and minor operations, elective and emergency procedures for men and women.

The aim of this study is to evaluate the effect of a 6-week Gold Standard Programme for alcohol cessation intervention in the perioperative period compared to the daily routine guidelines for patients with hazardous alcohol intake undergoing ankle fracture surgery.

Enrollment

70 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Drinking 21 or more drinks(one drink containing 12 g ethanol) per week for at least 3 months
Traumatic ankle fracture requiring internal fixation (osteosynthesis; more than just Kirschner threads or similar minor intervention)
Informed consent
Randomisation within 36 hours after entering the orthopaedic department

Exclusion criteria

Major trauma involving other fractures or major lesions,
Preoperative severe psychiatric disorders (including medicine addiction, severe alcohol dependence [defined as experience of delirium or seizures during abstinence from alcohol], dementia) or other conditions of reduced ability for giving informed consent
Pathological fractures
Pregnancy and lactation
Allergy to benzodiazepines, anaesthesia, pain treatment or disulfiram
Uncompensated chronic diseases (including fulminate cardiac or liver insufficiency, which are contraindications for disulfiram)
ASA score 4-5
Canceled operation
Withdrawal of informed consent