Alcohol Versus Chlorhexidine With and Without Water

NYU Langone Health

Status: Withdrawn

Conditions: Infection

Treatments: Other: Chlorhexidine + sterillium hand rub; Other: Chlorhexidine with water rinse; Other: Chlorhexidine without water rinse

Study type: Interventional

Funder types: Other

Identifiers

NCT02640469

14-00496

Details and patient eligibility

About

Currently at NYU institutions, providine-iodine and chlorhexidine medicated soaps are available as hand disinfection options. The purpose of this study is to determine the relative efficacy of traditional hand scrubs with chlorhexidine with or without rinsing with water after scrubbing is complete versus dry hand rubs with alcohol.

Full description

No current recommendations exist advocating the use of Providine-iodine or Chlorhexidine. Providine-iodine is safe and effective at reducing skin colonization with gram positive and negative bacteria, mycobacterium tuberculosis, fungi and viruses. Chlorhexidine similarly disrupts cellular membranes. It is bacteriocidal and bacteriostatic and has immediate and more lasting effect than iodine because it can bind to the stratum corneum of the skin and is effective against gram positive and negative organisms, lipophilic viruses and yeasts.

All subjects who are employees of the NYU Hospital for Joint Diseases and have experience with surgical hand disinfection will be asked to enroll. Subjects will be randomized into one of three study arms using an online randomizer: (1) the standard chlorhexidine with water rinse, (2) chlorhexidine without water rinse(experimental), and (3) standard chlorhexidine followed by sterillium hand rub. After hand disinfection protocol has been completed, each subject will have each hand cultured three times using a cotton swab culture stick and sent to the microbiology lab for processing

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Orthopedic resident or surgical employee of NY U
• Over 21 years of age
• Procedural knowledge of correct aseptic scrub technique

Exclusion criteria

• No surgical experience
• Under 21 years of age
• Refusal to consent

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 3 patient groups

Chlorhexidine with water rinse

Active Comparator group

Description:

This is a traditional method of disinfection used at NYU Hospital for Joint Disease. Following disinfection protocol, each subject will have hand cultured three times using a cotton swab culture and sent to microbiology for processing.

Treatment:

Other: Chlorhexidine with water rinse

Chlorhexidine without water rinse

Experimental group

Description:

This is an experimental method of disinfection. Following disinfection protocol, each subject will have hand cultured three times using a cotton swab culture and sent to microbiology for processing.

Treatment:

Other: Chlorhexidine without water rinse

Chlorhexidine + sterillium hand rub

Active Comparator group

Description:

This is a standard method of disinfection used at NYU Hospital for Joint Disease. Following disinfection protocol, each subject will have hand cultured three times using a cotton swab culture and sent to microbiology for processing.

Treatment:

Other: Chlorhexidine + sterillium hand rub