Status
Conditions
About
The purpose of this study is to evaluate the effect of ALDH2 mutation in radiation associating dermatitis or mucositis in head and neck cancer patients who accept chemoradiation therapy
Full description
One-site audit. The enrolled subject is confirmed by PIs
◦◦Source data is compared to external data sources medical records, either paper or electronic case report forms.
NCI CTCAE v5.0 for AE records
Patient recruitment according to inclusion criteria: 1. Newly diagnosed locally head and neck squamous cell carcinoma; 2. Apply for primary chemoradiation or adjuvant chemoradiation; 3. Signed informed consent
Sample size assessment: 60 subjects will be included in one year for total 120 subjects
Missing data to address situations where variables are reported as missing, unavailable, "non-reported," uninterpretable, or considered missing because of data inconsistency or out-of-range results
Fisher's exact test is for category comparison. Kaplan-Meier analysis is for survival analysis. AE grades will be analyzed according to NCI guideline. Two-side p < 0.05 is suggested significant.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
Exclusion criteria
Loading...
Central trial contact
Ling-Wei Wang, MD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal