Alendronate in the Prevention of Collapse of Femoral Head in Non-Traumatic Osteonecrosis

Kaohsiung Medical University

Status and phase: Unknown; Phase 4

Conditions: Non-Traumatic Osteonecrosis

Treatments: Drug: Alendronate

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00265252

fosamax 01

Details and patient eligibility

About

To determine the cumulative incidence of total hip replacement, time to event after treatment with Fosamax or placebo during the study peroid

Full description

To determine the cumulative incidence of total hip replacement and collpase of femoral head, time to event after treatment with Fosamax or placebo during the study peroid

Sex: All

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteonecrosis of femoral head
• be able to provide singed informed consent

Exclusion criteria

• prior bisphosphonate use
• pregnant or lactating woman
• bilateral hip replacement

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind