Allogene MSCs Transplantation in Liver for Patients With Chronic Liver Diseases Through Portal Vein by Ultrasound Guiding

Sun Yat-sen University

Status: Unknown

Conditions: Through Portal Vein by Ultrasound Guiding; Chronic Liver Diseases Patients; Allogene Transplantation

Study type: Observational

Funder types: Other

Identifiers

NCT01256138

SunYat-sen U 11-5-2

Details and patient eligibility

About

Allogene MSCs transplantation will be performed in patients with chronic liver diseases through portal vein by ultrasound guiding and therapeutic effects including short-term effects and long-term follow-up will be compared and investigated.

Enrollment: 60 estimated patients

Sex: All

Ages: 15 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. chronic liver diseases including: viral hepatitis, alcoholic liver disease, autoimmune liver disease.
2. age: 15-65 years old.

Exclusion criteria

1. pregnant women and women in lactation.
2. other systems and organs disfunction
3. space-occupying lesion were found in liver.
4. concurrent infection with HIV and other immunodeficiency diseases.
5. DIC and active bleeding were confirmed.

Trial design

60 participants in 2 patient groups

transplantation

control