Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.

Mahidol University

Status: Invitation-only

Conditions: Health-Related Behavior

Treatments: Behavioral: 50% sugar reduction

Study type: Interventional

Funder types: Other

Identifiers

NCT06678386

233/2567 (IRB1)

Details and patient eligibility

About

The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences. The main questions it aims to answer are:

• Does sweet intensity change after reducing daily sugar intake by 50% for 12 weeks?
• How does sweet intensity change after completing dietary modification for 8 weeks?
• Does individual daily sugar intake change after completing dietary modification for 8 weeks?

Researchers will compare reducing daily sugar intake by 50% for 12 weeks to an unmodified diet to see if sugar reduction can change sweet intensity.

Participants will:

• Reduce daily sugar intake by 50% or maintain an unmodified diet for 12 weeks.
• Visit the clinic three times for anthropometric measurements, sweet perception tests, and to complete questionnaires.
• Keep a diet record for a total of 15 days during the research period.

Enrollment: 58 estimated patients

Sex: All

Ages: 18 to 59 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• People with a fasting blood sugar level below 126 mg/dL or an HbA1C below 6.5% in the past 6 months, who are not currently being treated for diabetes.
• People who score 10 or more points on the sweet food consumption behavior questionnaire.
• People who are able to communicate in the Thai language.
• People who are able to chat and use video calls via the Line application.
• People who agree to modify their diet and beverages according to the recommendations of a dietitian.
• People who agree to undergo sweet taste testing, complete a food record, and fill out a questionnaire.

Exclusion criteria

• People with uncontrolled chronic conditions who have had changes in their treatment within the past 3 months.
• People with a history of severe illness in the past 6 months.
• People who regularly use medication, excluding contraceptives and vitamins.
• Pregnant women.
• People who have experienced a weight change of at least 10% over the past 3 months.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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58 participants in 2 patient groups

50% sugar reduction

Experimental group

Description:

Participants were advised by a dietitian to reduce their daily caloric intake from sugars by 50% for 12 weeks.

Treatment:

Behavioral: 50% sugar reduction

unmodified diet

No Intervention group

Description:

Participants maintained an unmodified diet.