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Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

H

Health Science Center of Xi'an Jiaotong University

Status

Unknown

Conditions

Irritable Bowel Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT01060527
xi'an JTU091202

Details and patient eligibility

About

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion criteria

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Trial design

60 participants in 3 patient groups

IBS-D
IBS-C
Controll

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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