Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse

Chulalongkorn University

Status: Completed

Conditions: The Comparison of Iodine in Saliva Between Gargle and Swab; The Retention of Iodine in Saliva Over the Time

Treatments: Other: Iodine gargle

Study type: Interventional

Funder types: Other

Identifiers

NCT06272019

HREC-DCU 2023-074

Details and patient eligibility

About

To compare the iodine remaining in saliva between gargle method and swab method

Full description

separate the participant in 2 groups group 1 use iodine gargle with gargle method, after 48 hours use iodine gargle with swab method group 2 use iodine gargle with swab method, after 48 hours use iodine gargle with gargle method The researcher will collect saliva before use iodine gargle and after use at time 0, 5, 10, 20, 30, 60, 120 minutes

Enrollment: 25 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Thai people
• no underlying disease, no pregnant
• at least 24 teeth
• No use iodine gargle
• No allergy to iodine and seafood
• No orthodontic and prosthetic treatment
• No ulcer and edentulous area
• Saliva flow rate in male (0.57+-0.3 ml/minute), in woman (0.41+-0.27 ml/minute)
• PI score lower than 0.6 (Green and vermillion index)

Exclusion criteria

• treatment orthodontic or prosthetic treatment currently
• Allergy to iodine between reach
• Can not participate

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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25 participants in 2 patient groups

Gargle method

Experimental group

Description:

the participant will use 0.2% iodine gargle with gargle method by hold in mouth 30 second and gargle 30 seconds after that spit out

Treatment:

Other: Iodine gargle

Swab method

Experimental group

Description:

the participant will use 0.2 iodine gargle with swab method by the researcher apply on mouth 1 minute without spit out

Treatment:

Other: Iodine gargle