Alveolar Bone Dehiscence and Fenestration Following Accelerated Maxillary Canine Retraction

Tanta University

Status: Enrolling

Conditions: Fenestration; Dehiscence

Treatments: Procedure: Combined decortication and PRP injection; Procedure: PRP injection

Study type: Interventional

Funder types: Other

Identifiers

NCT06500559

#R-ORTH-6-24-3117

Details and patient eligibility

About

Alveolar bone loss and fenestration are the most prevalent bone defects that often result in root exposure, gingival recession, and potential treatment relapse or failure. These issues present complications in orthodontic therapy. Hence, reducing the length of orthodontic therapy and minimizing the occurrence of these serious complications are highly important for orthodontic patients, particularly adults. platelet-rich plasma (PRP) injection and decortication are two promising methods for accelerated tooth movements. Thus, The aim of this study is to evaluate alveolar bone dehiscence and fenestrations after canine retraction, using alveolar decortication and PRP injection as two methods for accelerating tooth movements.

Enrollment: 24 estimated patients

Sex: All

Ages: 16 to 22 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age of the patients ranged from 16: 22 years old.
2. Malocclusion that requires extraction of the maxillary first premolar and canine retraction (e.g. class I bimaxillary dentoalveolar protrusion and class II div 1 malocclusion).
3. Maximum anchorage needed for the maxillary arch as a part of the orthodontic treatment plan.
4. Good oral hygiene and periodontal condition.

Exclusion criteria

1. Medically compromised patients.
2. Severe crowding in the maxillary arch.
3. Chronic intake of NSAIDs or any medication that interfere with OTM.
4. Previous orthodontic treatment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

group I: PRP injection

Experimental group

Description:

Accelerated maxillary canine retraction will be done after PRP injection in one random side of the maxillary arch while the other side serve as control

Treatment:

Procedure: PRP injection

group II: Combined decortication and PRP injection

Experimental group

Description:

Accelerated maxillary canine retraction will be done after combined decortication and PRP injection in one random side of the maxillary arch while the other side serve as control

Treatment:

Procedure: Combined decortication and PRP injection