Alzheimer's Disease Prevention Trial

National Institutes of Health (NIH) logo

National Institutes of Health (NIH)

Status and phase

Completed
Phase 3

Conditions

Alzheimer Disease
Memory Disorders

Treatments

Drug: Estrogen
Drug: Estrogen and Progesterone

Study type

Interventional

Funder types

NIH

Identifiers

NCT00000176
IA0018
RO 1AG15922-01

Details and patient eligibility

About

This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.

Full description

PREventing Postmenopausal memory loss and Alzheimer's with Replacement Estrogens (PREPARE) is a double-blind-placebo controlled trial to determine whether estrogen (or estrogen and progesterone) can delay the onset of memory loss or Alzheimer's Disease in elderly women with a family history of the disease.

Sex

Female

Ages

65+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy women 65 or older with a family history of memory problems not currently on estrogen.

Exclusion criteria

  • Significant neurological impairment
  • Current estrogen use
  • History of breast cancer

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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