Amino-acid Uptake After Meat Protein Intake

Bispebjerg Hospital

Status: Completed

Conditions: Amino Acid Metabolism

Treatments: Dietary Supplement: Meat protein absorption

Study type: Interventional

Funder types: Other

Identifiers

NCT03301337

BBH 135

Details and patient eligibility

About

The purpose of the project is to provide evidence for the use of hydrolysed meat protein (HMP) as a protein supplement for elderly who has difficulty meeting the recommended daily protein intake.

The study will investigate how the meat protein derived amino acids (from either HMP, steak or minced meat) are absorbed and released into the blood circulation of elderly persons. Hereby, the study will explore the the anabolic potential of HMP compared with common meat products.

Enrollment: 12 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Untrained

Exclusion criteria

• below 65 years of age
• BMI above 30
• Smokers
• Vegetarians
• Subjects with diabetes or other metabolic diseases
• Medical treatment affecting protein synthesis
• Gastro-intestinal problems, reduced liver or kidney function, elevated blood pressure, atherosclerosis
• More than 5 ours regular physical activity per week (except physical activity related to commuting)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 3 patient groups

Hydrolyzed meat protein

Experimental group

Description:

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Treatment:

Dietary Supplement: Meat protein absorption

Minced Meat

Experimental group

Description:

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Treatment:

Dietary Supplement: Meat protein absorption

Beef

Experimental group

Description:

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Treatment:

Dietary Supplement: Meat protein absorption