Amlodipine Diabetic Hypertension Efficacy Response Trial (ADHERE)

Viatris

Status and phase: Completed; Phase 4

Conditions: Hypertension

Treatments: Drug: Amlodipine

Study type: Interventional

Funder types: Industry

Identifiers

NCT00159692

A0531063

Details and patient eligibility

About

To evaluate the percentage of subjects that reach the diabetic hypertensive blood pressure goal of <130/80 with amlodipine versus placebo in subjects initially treated with quinapril or losartan.

Enrollment: 739 patients

Sex: All

Ages: 30 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Documented evidence of Type 2 diabetes as defined by the ADA guidelines and documented evidence of Hypertension (various SBP/DBP ranges).

Exclusion criteria

• A previous history or intolerance or hypersensitivity to calcium channel blockers, ARBs or ACE inhibitors.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind