Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina (ANISSA)

Viatris

Status and phase

Completed

Phase 4

Conditions

Myocardial Ischemia

Treatments

Procedure: Blood tests

Drug: iso- 5 - mononitrate

Drug: Amlodipine

Procedure: Exercise Stress Test

Study type

Interventional

Funder types

Industry

Identifiers

NCT00143195

A0531076

Details and patient eligibility

About

The objective of study is to compare the anti-ischemic efficacy and safety profiles of once daily amlodipine or isosorbide-5-mononitrate in the treatment of stable asymptomatic and symptomatic myocardial ischemia

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Outpatients > =18 years of age with diagnosed clinically stable angina pectoris

Exclusion criteria

Patients with congestive heart failure, clinically significant cardiovascular disease, standing systolic blood pressure of less than 100mmHg, concomitant anti-anginal therapies similar to sublingual NTG