AMNIOmics: A Prenatal Rapid Genome Validation Study

Mayo Clinic

Status: Withdrawn

Conditions: Family Members; Genetic Predisposition Suspected; Multiple Anomalies of Fetus; Amniocentesis Affecting Fetus or Newborn

Study type: Observational

Funder types: Other

Identifiers

NCT05834621

22-002719

Details and patient eligibility

About

The purpose of this study is to validate Whole Genome Sequencing (WGS) on amniotic fluid to reduce the time to diagnosis and enhance the care for the fetus/neonate.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Fetus with multiple anomalies/suspected genetic disease.
• Pregnant patient already planning on having an amniocentesis for another reason separate from this study.

Exclusion Criteria

• Parents under the age of 18.
• Parents lacking the capacity to consent.
• Institutionalized (i.e., Federal Medical Prison).