Amniotic Membrane Associated With Conjunctival Autograft Versus Conjunctival Autograft for Recurrent Pterygia

Federal University of São Paulo

Status and phase: Unknown; Phase 1

Conditions: Recurrent Pterygia

Treatments: Procedure: Conjunctival autograft versus conjunctival autograft treatment for recurrent pterygia

Study type: Interventional

Funder types: Other

Identifiers

NCT00802620

0616/04

Details and patient eligibility

About

The purpose of this study is to compare amniotic membrane associated with conjunctival autograft versus conjunctival autograft alone in the treatment of recurrent pterygia.

Full description

Patients with recurrent pterygia without symblepharon were randomly assigned to undertake pterygium excision followed by amniotic membrane associated with a small conjunctival autograft (2x3mm) or conjunctival autograft (approximately 5x8mm) alone. The patients were examined after 1, 7, 30, 90, 180 and 360 days after the surgery. Recurrence was considered as a fibrovascular ingrowth of 1.5 mm or more beyond the limbus with conjunctival drag.

Enrollment: 40 patients

Sex: All

Ages: 15 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Recurrent pterygium

Exclusion criteria

• Less than 15 year of age
• Symblepharon
• Glaucoma,
• Ocular Allergy
• Ocular surface disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)