Amniotic Membrane for Recurrent Macular Hole

Minia University

Status: Unknown

Conditions: Macula Hole; Myopic Macular Degeneration; Retinal Detachment

Treatments: Procedure: Recurrent opened macular hole

Study type: Interventional

Funder types: Other

Identifiers

NCT03528122

63 2/2018

Details and patient eligibility

About

Macular hole surgery were tried by different surgeons using many techniques with different successes but still there were many recurrences. In this study the investigators try to close these distinct types including recurrent holes using pre-prepared amniotic membrane.

Full description

It is an interventional study of using amniotic membrane graft for closure of macular hole associated retinal detachment in patient who had a previous failed macular surgery.

Enrollment: 20 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with history of opened macular hole after previous pars plana vitrectomy and internal limiting membrane (ILM) peeling for treatment of myopic macular hole were included.
• Opened holes after 1 month of the surgery.
• Myopic macular holes only were included (Refraction of more than _6 D and/or axial length of more than 26 mm).

Exclusion criteria

• All other causes of macular hole (traumatic and idiopathic)
• Patients with diseases that can affect visual outcome (Diabetic retinopathy, choroidal neovascularization, age-related macular disease and advanced glaucoma patients.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Recurrent opened macular hole

Experimental group

Description:

Pars plana vitrectomy with internal limiting membrane peel if not peeled in the first surgery and application of amniotic membrane graft

Treatment:

Procedure: Recurrent opened macular hole