Amphotericin B Treatment in Visceral Leishmaniasis

Banaras Hindu University

Status: Completed

Conditions: Visceral Leishmaniasis

Treatments: Drug: Amphotericin B deoxycholate given as daily administration

Study type: Interventional

Funder types: Other

Identifiers

NCT00310505

SS01MZP03

Details and patient eligibility

About

This study is being conducted to assess the safety and efficacy of amphotericin B deoxycholate in doses of 0.75 mg/kg or 1.0 mg/kg for 15 doses. In each arm the drug is given in the conventional way every alternate day against the daily administration regimen being tested.

Full description

This study is being conducted to assess the safety and efficacy of amphotericin B deoxycholate in doses of 0.75 mg/kg or 1.0 mg/kg for 15 doses. In each arm the drug is given in the conventional way every alternate day against the daily administration regimen being tested.

Sex: All

Ages: 2 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parasitologically proved kala-azar

Exclusion criteria

• HIV positive serology

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)