An Attempt to Find Out Root Cause of a Pain Producing Knee Disease

DR R C Agrawal

Status: Completed

Conditions: Arthroplasty; Knee; Knee Osteoarthritis

Treatments: Other: Contracture Correction Therapy

Study type: Observational

Funder types: Other

Identifiers

NCT04496440

1001

Details and patient eligibility

About

This study was focused on a type of arthritis (knee) in which patients develop pain with disabilities in sitting and walking etc. In advance stage the person is bereft of his/her personal physical activities. The prevalent treatment is temporary and dis-satisfactory. A new treatment was designed and a trial was conducted on 125 patients (100 in the trial group, 25 in the control group) for a duration of six months.

Full description

The study was focused on establishing the cause and treatment of a painful knee joint disease (Primary Osteoarthritis Knee = OA Knee). At present the cause and treatment are not known. The study was based on a hypothesis, designing a treatment and testing it through a clinical trial. This established that the deficient full flexion or deficient full extension of knee joints, producing contracture in their capsules was the cause and the correction (Contracture Correction Therapy = CCT) was the cure of the disease. The correction was carried out by passive flexion or passive extension of affected knee through eight body postures designed specifically during the study.

To test the efficacy a multi-centre, multi surgeon six months study on 125 patients was carried out, patients were divided into Trial and Control groups. The effects were measured by primary outcome measure - The Western Ontario and McMaster Universities Arthritis Index (WOMAC) score and other measure EuroQol-Visual Analogue Scales (EQ-VAS) score, DFF*, DFE^ at 0, 6 ,12 and 24 weeks.

The "Intervention" for 1st group was CCT and for the 2nd group was "No intervention".

* Deficient full flexion

^ Deficient full extension

Enrollment: 138 patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age =>30 years
• Knee pain which appeared without any apparent cause, exacerbated by exertion and subsided by rest.
• Presence of limited morning stiffness
• No history of infection, inflammation or trauma to rule out secondary OA
• Disability in sitting, climbing stairs or walking

Exclusion criteria

• Backache
• Leg pain (e.g. sciatica)
• Inability to lie supine (e.g. kyphosis)
• Inability to lie prone (e.g. central obesity)

Trial design

138 participants in 2 patient groups

Trial Group

Description:

Contracture correction therapy

Treatment:

Other: Contracture Correction Therapy

Control Group

Description:

No new intervention, patients continued with the previous treatment.