An Automated, Tailored Information Application for Medication Health Literacy

Nova Southeastern University (NSU)

Status: Completed

Conditions: Human Immunodeficiency Virus I Infection

Treatments: Behavioral: Tailored Information

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01304186

R21MH086491 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to evaluate the acceptability and efficacy of a computer-based tailored information application designed to promote health literacy in persons treated for HIV infection. The study hypothesis is that the application will be acceptable and usable for persons treated for HIV infection, and will improve their levels of adherence to antiretroviral medication treatment.

Full description

Health literacy is a critically important problem in improving the effectiveness of health care interventions. Patient behaviors essential to the successful treatment of HIV infection, such as high levels of medication adherence, may depend on patients understanding how to take medication, how to solve medication-related problems, and how to cope with medication side effects. An approach that has shown promise in promoting behavior change in HIV+ persons is the Information-Motivation-Behavior Skills (IMB) model. The intervention proposed in this application will implement a health literacy intervention based in part on insights about behavior change drawn from studies of this model. The purpose of the proposed research is to implement this intervention via a computer-based and automated tailored information application. Participants will first complete an automated computer-administered self interview (ACASI) that will assess medication knowledge, disease knowledge likely to be related to motivation, and problem solving skills. Results of this assessment will feed forward to an automated training application that provides individually-tailored training on these topics. This computer-based program will provide training, test understanding, and if necessary reteach and retest. It will also provide printed information for participants to take home to provide ongoing prompts. This study will comprise two phases. In the first, the program will be developed and tested with potential users to assess its usability and detect problems with the wording of materials. In the second phase, participants' health literacy and cognitive status will be evaluated, their adherence to a medication for HIV infection will be assessed using electronic monitoring, and the effects of the program on their adherence will be tested.

Enrollment: 124 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18 years or older
• Currently treated with at least one medication for HIV infection
• No change in target medication anticipated in the next two months
• Able to participate in the study intervention in English

Exclusion criteria

• Psychiatric or cognitive disorder of severity sufficient to make the potential participant unable to provide informed consent.
• Not able to participate in the intervention using English.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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124 participants in 1 patient group

Tailored Information

Experimental group

Description:

Participants in this arm receive the computer-based tailored information application that focuses on improving health literacy related to treatment of HIV infection.

Treatment:

Behavioral: Tailored Information