An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit

Fujian Medical University (FJMU)

Status: Completed

Conditions: Neuromyelitis Optica Spectrum Disorders

Study type: Observational

Funder types: Other

Identifiers

NCT04388072

LS2019-004-02

Details and patient eligibility

About

The diagnostic cohort study could will be use to verify the clinical performance of the AQP4 -immunoglobulin G detection kit and whether it has a good correlation with the clinical diagnosis results. The applicability and accuracy of the kit in clinical diagnosis will be verified according to the measured data.

Enrollment: 200 patients

Sex: All

Ages: 14 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. The patients who were diagnosed with NMOSD , and the cell-based assay was used to determine the AQP4-IgG-seropositive patients;
2. AQP4-IgG is negative in health people with age and sex matching and determined by cell-based assay;
3. Female or male, age 14-80;
4. Patients or authorized family members volunteered to participate in this study and signed informed consent.

Exclusion criteria

1. Patients with coagulation disorders;
2. Infection-related encephalitis;
3. Immune-related encephalitis;
4. A patient with severe mental illness who cannot cooperate clinically;
5. A patient with severe jaundice.