An Exercise Intervention to Improve Overall Brain Health

The University of Alabama at Birmingham

Status: Completed

Conditions: Brain Care Score; Hypertension; BMI; Exercise

Treatments: Behavioral: Exercise Intervention to improve overall Brain Health

Study type: Interventional

Funder types: Other

Identifiers

NCT06035094

2027708 (Other Grant/Funding Number)

IRB-300011511

Details and patient eligibility

About

The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a body mass index ≥ 25 kg/m2. The main question[s] it aims to answer are:

• To test the effect of moderate vs intensive exercise on Brain Care Score outcomes.
• To ascertain the differential impact of moderate vs high intensity exercise in reducing hypertension and its downstream effects.

Enrollment: 35 patients

Sex: All

Ages: 35 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosed with hypertension
• have a body mass index ≥ 25 kg/m2
• are between the ages of 35-65 years old
• access to a smart phone that allows installation of 2 two applications that record your workouts
• pass a fitness evaluation.

Exclusion criteria

• do not have hypertension
• weight over 300 lbs
• unable to pass the fitness evaluation
• BMI less than 25kg/m2

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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35 participants in 3 patient groups

High Intensity Interval Training (HIIT) exercise group,

Experimental group

Description:

Participants will be asked to exercise independently 4 days/week for 10 weeks, following a high intensity interval training (HIIT) protocol.

Treatment:

Behavioral: Exercise Intervention to improve overall Brain Health

Moderate Intensity Training (MIT) exercise group

Experimental group

Description:

Participants will be asked to exercise independently 4 days/week for 10 weeks, following a moderate intensity training (MIT) protocol.

Treatment:

Behavioral: Exercise Intervention to improve overall Brain Health

Control exercise group

Active Comparator group

Description:

Participants will be advised to follow the American Heart Association (AHA) guidelines on exercise.

Treatment:

Behavioral: Exercise Intervention to improve overall Brain Health