An Exploratory Study to Investigate the Inflammatory Response During a Cold Sore Episode

GlaxoSmithKline (GSK)

Status and phase: Completed; Phase 1

Conditions: Herpes Labialis

Treatments: Device: Acyclovir patch; Device: Placebo patch

Study type: Interventional

Funder types: Industry

Identifiers

NCT01653509

E7411153

Details and patient eligibility

About

This study will treat approximately 24 participants who experience cold sores. Patches will be applied to the cold sore for up to ten days, and the symptoms will be measured during daily clinic visits using non-invasive measurement techniques.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Participants who are susceptible to cold sores that reactivate when exposed to ultraviolet (UV) light

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Test patch

Experimental group

Description:

Patch containing acyclovir applied to cold sore

Treatment:

Device: Acyclovir patch

Placebo patch

Placebo Comparator group

Description:

Patch without acyclovir applied to cold sore

Treatment:

Device: Placebo patch