Αn Information System for Symptom Diagnosis and Improvement of Attention Deficit Hyperactivity Disorder (ADHD360)

Aristotle University Of Thessaloniki

Status: Completed

Conditions: Attention Deficit Hyperactivity Disorder

Treatments: Other: ADHD360 platform: An intervention intergrating a serious game along with a mobile application for daily behavioral monitoring.

Study type: Interventional

Funder types: Other

Identifiers

NCT04362982

5162.18.12.2019

Details and patient eligibility

About

ADHD360 will be an innovative integrated platform for early ADHD diagnosis and intervention against its symptoms. In the core of the platform design there will be a serious game along with a mobile application to monitor behavior and to evaluate the intervention.

Full description

The ADHD360 project develop an integrated platform having as core elements a serious game along with a mobile application for monitoring of ADHD behaviors in a SMART (Specific, Measurable, Attainable, Realistic and Timely) way. The design of the serious game is based on both Diagnostic and Statistical Manual of Mental Disorders (version V(American Psychiatric Association, 2013)) along with neuropsychological tools, easily transferred to game, on a specific ADHD behavior. The primary objective of the project is to explore whether the game analytics along with the monitoring data could discriminate the ADHD from non-ADHD users. The secondary objective is to use the platform as an intervention. To this scope, a two-phase pilot study will be performed recruiting at least twenty (20) participants (10 ADHD; 10 non-ADHD) with ages ranging from 7 to 16 years. In the first stage, participants will undergo a neuropsychological evaluation as well as interact with the serious game two times (30-45 minutes/each time). After all participants have completed the first part of the pilot tests, a preliminary analysis of the data will be carried out using modern Machine Learning Methods in order to explore the discriminating capacity of the game. In the second stage, participants will interact with the platform for ten (10) weeks in total (2-3 times/30-45 minutes each). At the end of the second stage, the participants will undergo a neuropsychological evaluation following the procedures of the first one. The partners involved in the implementation of the project are the Intelligent Systems Lab (School of Computer Science, AUTH), the MEDPHYS Laboratory (School of Medicine, AUTH) and the Second Method (TSM) company. The partners cover the expertise required in data analysis, machine learning, medical record keeping, software development and game design (gamification). ADHD360 is co-financed by the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH - CREATE - INNOVATE [Τ1ΕΔΚ-01680].

Enrollment: 43 patients

Sex: All

Ages: 7 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (1) Participants should be between 7 and 16 years old
• (2) Diagnosed ADHD by an approved body of Ministry of Health
• (3) Participants willing to follow the study protocol and procedures
• (4) Participants with ADHD symptoms that they are not induced by an organic disease
• (5) Participants' parents voluntarily provided written consent for their children's participation in the study.

Exclusion criteria

• (1) Participants in ADHD group having other disorders apart from ADHD
• (2) Parents who refuse to give written consent for their children's participation in the study.

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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43 participants in 2 patient groups

ADHD

Experimental group

Description:

In the first part of the clinical trials, ADHD cohorts are going to undergo a neuropsychological assessement. Moreover, they will interact with the serious game twice (30-45 minutes/each time). In the second part, participants will interact with game two or three times per week (30-45 minutes/each time). Finally, a neuropsychological assessment will be administered following the procedures of the first one.

Treatment:

Other: ADHD360 platform: An intervention intergrating a serious game along with a mobile application for daily behavioral monitoring.

non-ADHD

Active Comparator group

Description:

Non-ADHD group will follow the same procedures as the experimental one.

Treatment:

Other: ADHD360 platform: An intervention intergrating a serious game along with a mobile application for daily behavioral monitoring.