An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors

M.D. Anderson Cancer Center

Status and phase

Active, not recruiting

Early Phase 1

Conditions

Digestive System Neuroendocrine Tumor G1

Metastatic Carcinoid Tumor

Carcinoid Syndrome

Carcinoid Tumor

Treatments

Procedure: Dual-Energy Computed Tomography

Study type

Interventional

Funder types

Other

Identifiers

NCT04993261

2014-0578 (Other Identifier)

NCI-2019-02477 (Registry Identifier)

Details and patient eligibility

About

This trial studies the use of a special type of computed (CT) scan called dual energy CT in detecting gastrointestinal carcinoid tumors. CT is an imaging technique that uses x-rays and a computer to create images of areas inside the body. Dual energy computed tomography is a technique used during routine CT scans to help obtain and process the image after the scan is complete. Doctors want to learn if dual energy computed tomography can help improve the detection of carcinoid tumors during routine CT scans.

Full description

PRIMARY OBJECTIVES:

I. Evaluate prospectively the sensitivity and specificity of dual energy computed tomography (CT) in detecting primary gastrointestinal (GI) carcinoid.

OUTLINE:

Patients undergo one dual energy CT scan during scheduled CT scan.

Enrollment

71 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with: clinical features of carcinoid syndrome (or) increased serum and urinary markers suggestive of carcinoid (or) endoscopic biopsy proven carcinoid (or) metastases which are biopsy proven as carcinoid.
Patient is scheduled to have a clinically indicated staging CT exam.
Patients who have signed their informed consent form to undergo the study.

Exclusion criteria

Patients who have already had their primary GI carcinoid resected.
Contraindication to intravenous contrast agents (e.g. allergy, renal failure, dialysis, pregnancy etc.).
Pregnant patients.