An ISO Principle-Based Music Intervention for Reducing Stress, Anxiety, and Depression (ISO4SAD)

Shanghai Mental Health Center

Status: Enrolling

Conditions: Depression in Adults; Anxiety; Stress

Treatments: Behavioral: ISO Principle Music Intervention; Behavioral: Compensation Principle Music Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT07055061

THU0420251002

62101324 (Other Grant/Funding Number)

Details and patient eligibility

About

This study aims to evaluate the effectiveness of a music-based intervention, guided by the ISO principle, in reducing stress, anxiety and depression induced by work, family or others among adults. The ISO principle suggests that emotional regulation can be supported by gradually modifying the emotional characteristics of music to help individuals transition to a desired emotional state.

Participants in this study will be randomly assigned to either a music intervention group or a control group. The intervention group will receive personalized music playlists designed to help reduce stress, anxiety and depression. The control group will not receive any music intervention during the same period.

Outcomes will be measured using self-report questionnaires assessing stress, emotional state, and well-being. The study is designed to contribute to the development of accessible, non-invasive stress management tools using music as a behavioral intervention.

Enrollment: 200 estimated patients

Sex: All

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Has completed education at the associate degree level or higher
• Has at least one year of stable full-time work experience
• Maintains a regular and stable daily routine

Exclusion criteria

• Current or recent use of medication or history of surgical treatment
• History of psychiatric disorders
• Hearing impairments
• Female participants who are currently pregnant or breastfeeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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200 participants in 2 patient groups

ISO Group

Experimental group

Description:

Participants in this group will receive a music intervention based on the ISO principle. The playlists are designed to gradually shift emotional states by starting with music that matches the participant's current mood and progressing toward tracks that reflect the desired emotional state, aiming to promote stress reduction and emotional regulation.

Treatment:

Behavioral: ISO Principle Music Intervention

Compensation Group

Active Comparator group

Description:

Participants in this group will receive a music intervention based on the compensation principle. The playlists directly contrast the participant's current emotional state by immediately introducing music that represents the target mood (e.g., relaxing music for a stressed state), with the aim of counteracting stress and promoting emotional change.

Treatment:

Behavioral: Compensation Principle Music Intervention