An Observational Study of Japanese Participants With X-linked Retinitis Pigmentosa

Janssen (J&J Innovative Medicine)

Status: Completed

Conditions: X-Linked Retinitis Pigmentosa

Study type: Observational

Funder types: Industry

Identifiers

NCT04868916

CR108926

74765340RPG0001 (Other Identifier)

Details and patient eligibility

About

The purpose of the study is to identify a cohort of Japanese participants with X-linked retinitis pigmentosa (XLRP) associated with pathogenic variants in the retinitis pigmentosa GTPase regulator (RPGR) gene and to investigate their associated phenotype.

Enrollment: 15 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Have RPGR-associated retinal dystrophy
• Are able to give informed consent or assent, with the guidance of their parent/guardian where appropriate
• Are able to undertake age-appropriate clinical assessments as specified in the protocol

Exclusion criteria

• Are unable or unwilling to undertake consent or clinical testing
• Participated in another research study and had intraocular surgery within 3 months of screening
• Significant ophthalmologic diseases

Trial design

15 participants in 1 patient group

Participants with X-Linked Retinitis Pigmentosa (XLRP)

Description:

Participants with confirmed diagnosis of XLRP associated with pathogenic variants in retinitis pigmentosa GTPase regulator (RPGR) in the Japanese population will be enrolled in the study and the data will be collected and observed. The primary data source for this study will be the medical records of each participant.