An Observational Study of Subcutaneous Implantable Cardioverter Defibrillator in Patients with Hypertrophic Cardiomyopathy At High Risk of Sudden Cardiac Death

National Center for Cardiovascular Diseases

Status: Active, not recruiting

Conditions: HCM - Hypertrophic Cardiomyopathy; S-ICD System (implantable Defibrillator)

Study type: Observational

Funder types: Other

Identifiers

NCT06604169

S-ICD in HCM

Details and patient eligibility

About

1. To observe the failure rate of S-ICD screening in HCM patients at high risk of SCD.
2. To observe the incidence of IAS in HCM patients with S-ICD implantation and explore the related factors of IAS.

Full description

The study was a multicenter, prospective, observational study that prospectively included HCM patients assessed as meeting the ICD implantation indication at Fuwai Hospital and National Collaborative Hospitals from July 1, 2024 to June 30, 2027, for pre-operation screening of S-ICD, and follow-up of patients eventually implanted with S-ICD.

Enrollment: 589 estimated patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HCM patients assessed as meeting the ICD implantation indication

Exclusion criteria

• Combined with bradycardia with pacing indications;
• Frequent monomorphic ventricular tachycardia require ATP therapy;
• With indications of CRT;
• Combined with other diseases, life expectancy is less than 1 year.