An Observational Study on the Relationship Between Tear Metabolomics and POD

Chongqing Medical University

Status: Completed

Conditions: Postoperative Delirium

Study type: Observational

Funder types: Other

Identifiers

NCT05548153

tear and delirium

Details and patient eligibility

About

To explore the correlation between tear metabolomics and POD. The purpose of this study was to compare the results of tear metabolomics between POD and non-POD elderly patients undergoing abdominal surgery, to clarify the correlation between tear metabolomics and POD, and to find tear markers related to POD.

Enrollment: 150 patients

Sex: All

Ages: 65 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 65-90 years old;
• ASA I-III;
• patients who plan to undergo elective abdominal surgery under general anesthesia;
• Volunteer to participate in this study and sign informed consent.

Exclusion criteria

• patients with known mental illness or lack of communication or cognitive impairment before operation;
• severe vision, hearing, language impairment or other reasons unable to communicate with visitors;
• severe dysfunction of important organs such as heart, brain, lung, liver, kidney, etc.;
• long-term use of sedatives, antidepressants or alcoholism;
• patients with severe postoperative complications and admitted to intensive care unit;
• patients who refused or failed to complete the cognitive function test.
• patients who could not cooperate with the study for any other reason