An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data

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Member Companies of the Opioid PMR Consortium

Status

Completed

Conditions

Opiate Addiction
Opioid-Related Disorders
Drug Abuse
Narcotic Abuse

Treatments

Other: Algorithm to identify patients experiencing opioid abuse/addiction

Study type

Observational

Funder types

Other
Industry

Identifiers

NCT02667262
3033-7 (Other Identifier)
Observational Study 3033-7

Details and patient eligibility

About

The purpose of this study is to develop and validate a classification model based entirely on medical claims data that can be used to identify patients experiencing prescription opioid abuse/addiction among patients receiving extended-release (ER) and/or long-acting (LA) opioids

Full description

The most widely available information about patient care and conditions is that contained in medical claims data. If such data can be used to develop a model for identifying patients experiencing prescription opioid abuse/addiction it could be widely applied to patient populations throughout the United States. A study recently conducted at Group Health comparing International Classification of Disease, Ninth edition (ICD-9) coding for opioid abuse/addiction to textual mentions in clinical notes describing abuse/addiction found that ICD-9 codes were 64% sensitive and 96% specific in their ability to identify patients experiencing opioid abuse/addiction (compared to evidence from clinical notes). This Group Health study considered codes for abuse (305.x) and addiction (304.x) equivalent because clinicians' usage of these codes did not differentiate well between abuse and addiction. Needed are methods that can accurately identify patients experiencing opioid abuse/addiction based on widely available claims data. This study will not evaluate opioid misuse because this will be captured by instruments in a prospective study of pain patients (Study 1A) using a combination of adapted validated instruments, and other new instruments that will be evaluated in post-marketing requirement (PMR) Study 2, plus medical record review to supplement questionnaire-based measurement of misuse, abuse and addiction with aberrant behaviors and physician text entries in the medical records.

Enrollment

1,667 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Age ≥ 18 years
  2. Receipt of at least a 60 day's supply of ER/LA opioid analgesics within a 90-day period (including transdermal or oral opioids but excluding buprenorpine)
  3. Minimum of at least two years continuous enrollment in Group Health integrated group practice (IGP)

Exclusion criteria

  1. Residence in a nursing home at any time during the study period
  2. Enrollment in a hospice care program at any time during the study period

Trial design

1,667 participants in 1 patient group

Extended Release and/or Long-Acting Opioids
Treatment:
Other: Algorithm to identify patients experiencing opioid abuse/addiction

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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