Anal Fistula and Microdialysis - What is Yet to Learn?

University Hospital, Umeå

Status: Enrolling

Conditions: Anal Fistula

Treatments: Device: OnZurf Probe, Senzime AB, Uppsala, Sweden

Study type: Interventional

Funder types: Other

Identifiers

NCT04178707

UMUmea

Details and patient eligibility

About

Anal Fistula can be a challenging condition to treat. Microdialysis has never before been used to examine the inner environment of anal fistula. This is now going to be performed.

Full description

Patients with anal fistula can have a reduced quality of life for years do to fistula complications. This condition is not well researched and more knowledge is needed to provide better care. Microdialysis has been used to study other organs of the body such as the brain, liver and GI-tract. Upcoming study is going to study the inner environment of the anal fistula in regards to lactate, pyruvate and glucose.

The study group is patients with anal fistula that with a need for seton treatment. Measurements with microdialysis will take place before operative procedure and one month after getting their seton inserted.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• over 18 years of age
• to be able to understand and accept the terms of study

Exclusion criteria

• age under 18
• dementia, language barrier

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Intervention

Other group

Description:

Using microdialysis the patients inner enviorment of the anal fistula will be measured - levels of lactate, glucose and pyruvate.

Treatment:

Device: OnZurf Probe, Senzime AB, Uppsala, Sweden