Anal Fistula Plug Versus Endorectal Advancement Flap (AFPERAF)

University of Zurich (UZH)

Status: Unknown

Conditions: Anal Fistula

Treatments: Procedure: Endorectal Advancement Flap; Procedure: Anal Fistula Plug

Study type: Interventional

Funder types: Other

Identifiers

NCT01931371

KEK-ZH-Nr. 2013-XYZ (Other Identifier)

AFPERAF

Details and patient eligibility

About

The purpose of this study is to determine whether anal fistula plug or endorectal advancement flap is more successful in the treatment of anal fistulas and compared both procedures with regards to cost.

Full description

A detailed analysis will be performed to determine independent predicting factors of recurrence and of higher costs.

Enrollment: 71 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (18 years of age or more)
• Single anal fistula
• Surgically treated with anal fistula plug or endorectal advancement flap

Exclusion criteria

• Children or adolescents
• Pregnancy
• Patients treated with setons alone

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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71 participants in 2 patient groups

Recurrent anal fistula

Active Comparator group

Description:

Patients with a complex anal fistula that recurred after surgery with an Anal Fistula Plug or and Endorectal Advancement Flap

Treatment:

Procedure: Anal Fistula Plug

Procedure: Endorectal Advancement Flap

No recurrence of anal fistula

Active Comparator group

Description:

Patients with a complex anal fistula that did not develop recurrence after surgery with an Anal Fistula Plug or and Endorectal Advancement Flap

Treatment:

Procedure: Anal Fistula Plug

Procedure: Endorectal Advancement Flap