Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Peking University

Status and phase: Unknown; Phase 4

Conditions: Postoperative Pain

Treatments: Drug: Nalbuphine; Drug: Morphine

Study type: Interventional

Funder types: Other

Identifiers

NCT03288428

NABUMORPHINE

Details and patient eligibility

About

to compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy.

Full description

To compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy, by using patient controlled analgesia postoperatively, a randomized, double blind clinical trial. Patients undergoing elective Laparoscopic myomectomy are randomly divided into two groups: nalbuphine and morphine groups. All patients are under general anesthesia with routine methods. The nalbuphine group receive postoperative patient controlled analgesia using nalbuphine 30mg/120ml, while the morphine group receive postoperative patient controlled analgesia using morphine 60mg/120ml. Perioperative parameters are to be collected to compare the two groups.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective Laparoscopic myomectomy patients 24hr post-operative patient controlled analgesia analgesia no mild or severe liver or renal disfunction

Exclusion criteria

• can't understand patient controlled analgesia device refuse trial

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups

nalbuphine

Experimental group

Description:

using nalbuphine for patient controlled analgesia

Treatment:

Drug: Nalbuphine

morphine

Active Comparator group

Description:

using morphine for patient controlled analgesia

Treatment:

Drug: Morphine