Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery

University of Liege

Status: Unknown

Conditions: Surgery of Abdominoplasty With Flank Liposuction

Treatments: Procedure: Continuous wound infusion; Procedure: Transverse abdominal plan block

Study type: Interventional

Funder types: Other

Identifiers

NCT01862354

2013-00017214-14 2013/9

2013-000172-14 (EudraCT Number)

Details and patient eligibility

About

The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of Abdominoplasty Combined With Flank Liposuction. Local anesthetics products used are ropivacaine combined with clonidine. Similar amount of local anesthetics and clonidine are used.

Full description

In a first group, patients receive, after induction of anaesthesia and before surgery, a TAP block (transverse abdominal plan block) with 3mg/kg Ropivacaine 0.5% (maximum 200 mg) and 150 microg Clonidine.

In a second group, before skin closure, a multiholes catheter was inserted beyond the skin. 20 mg Ropivacaine 0.2% added with 150 microg Clonidine was injected as bolus dose through this catheter followed by a continuous infusion of Ropivacaine 0.2% 10ml per hour during the following 9 hours (total dose of 200 mgr).

Enrollment: 50 estimated patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for abdominoplasty combined with flank liposuction

Exclusion criteria

• Allergy to local anesthetics or clonidine
• Coagulation disorders
• History of chronic pain
• Alcohol or drugs dependance
• Refusal of the patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Group TAP block

Active Comparator group

Description:

Patients in this group received a transverse abdominal plan block with local anesthetics and clonidine as postoperative analgesia.

Treatment:

Procedure: Transverse abdominal plan block

Group : Continuous wound infusion

Active Comparator group

Description:

Patients in this group received continuous wound infusion with local anesthetics and clonidine as postoperative analgesia.

Treatment:

Procedure: Continuous wound infusion