Analgesic Effect of Etoricoxib (ARCOXIA®) 120MG During Retinal Laser Photocoagulation

University of Sao Paulo

Status: Completed

Conditions: Proliferative Diabetic Retinopathy

Treatments: Drug: Etoricoxib (Treatment Group); Drug: placebo (Control Group)

Study type: Interventional

Funder types: Other

Identifiers

NCT00529594

519/06

Details and patient eligibility

About

The study wants to show if the medication etoricoxib 120 mg have reduces the patients pain during the laser photocoagulation, for diabetic retinopathy.

Full description

To do so we compare two group of patients, randomized 1:1, one use the medication(etoricoxib) and other use placebo and they quantify the pain using the Pain visual analogue scale

Enrollment: 44 patients

Sex: All

Ages: 17+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with diabetic retinopathy that needs laser photocoagulation for the first time

Exclusion criteria

• Younger than 17
• Signs and symptoms of liver dysfunction or abnormal liver function tests
• Gastrointestinal diseases
• Pregnant women
• Edema
• Pre-existing cardiac insufficiency

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

44 participants in 2 patient groups, including a placebo group

Control Group

Placebo Comparator group

Description:

Patients who received placebo

Treatment:

Drug: placebo (Control Group)

Treatment Group

Active Comparator group

Description:

Patients who received etoricoxib 120 mg

Treatment:

Drug: Etoricoxib (Treatment Group)