Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus

TC Erciyes University

Status and phase: Completed; Phase 4

Conditions: Postoperative Pain

Treatments: Procedure: intraarticular dexamethasone; Procedure: interscalene dexamethasone; Procedure: serum phsyologic

Study type: Interventional

Funder types: Other

Identifiers

NCT02026050

2013/639

Details and patient eligibility

About

the aim of this study was to investigate the analgesic efficacy of intra articular dexamethasone administration for arthroscopic shoulder surgery.

Full description

shoulder surgery can be very painful and interscalene brachial plexus block is the gold standard in the management of acute pain after shoulder surgery. various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexamethasone are frequently used for this purpose. dexamethasone has also been found the prolong the duration of lidocaine axillary blocks and intravenous regional anaesthesia. intraarticular administration of medicines can be used for management of joint pain and opioids , local anaesthetics and dexamethasone are used for this purpose.In addition, there are no studies available to compare the different treatment methods used in clinical practice directly.

Enrollment: 75 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• between 18-65 years
• arthroscopic shoulder surgery
• no known allergies to drugs
• ASA 1-2 patients

Exclusion criteria

• history of diabetes
• history of chronic pain treatment
• pregnancy
• severe bronchopulmonary disease
• systemic glucocorticoid use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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75 participants in 3 patient groups, including a placebo group

intraarticular dexamethasone

Active Comparator group

Description:

interscalene brachial plexus block was preoperative performed 30 ml 0.5 % bupivacaine+ 2 ml serum phsyologic and after surgery 2 ml 8 mg dexamethasone+ 8 ml serum phsyologic administration for intraarticular

Treatment:

Procedure: intraarticular dexamethasone

interscalene dexamethasone

Active Comparator group

Description:

interscalene brachial plexus was preoperative performed 30 ml 0.5 % bupivacaine added 2 ml 8mg dexamethasone and after surgery 10 ml serum phsyologic administration for intraarticular

Treatment:

Procedure: interscalene dexamethasone

serum phsyologic

Placebo Comparator group

Description:

interscalene brachial plexus block was preoperative performed 30 ml 0.5 % bupivacaine+ 2ml serum phsyologic and after surgery 10 ml serum phsyologic administration for intraarticular

Treatment:

Procedure: serum phsyologic