Analgesic Effect of Perineural Fentanyl Additive to Local Anesthetics in Femoral Nerve Block

Chonnam National University

Status: Unknown

Conditions: Postoperative Pain

Treatments: Drug: Fentanyl; Drug: rocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02331576

CNUHH-2014-141

Details and patient eligibility

About

The purpose of this study is to evaluate the analgesic efficacy of perineural fentanyl combined with local anesthetics in the post operative pain control with continuous femoral nerve block after total knee arthroplasty.

Enrollment: 100 estimated patients

Sex: All

Ages: 60 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who scheduled to receive knee arthroplasty with general anesthesia
• ASA physical status 1 or 2

Exclusion criteria

• allergy to drug
• refuse to the study
• ASA physical status 3 and 4
• history of drug abuse
• cognitive disfunction such as dementia
• patients who do not adequate for general anesthesia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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100 participants in 2 patient groups, including a placebo group

rocaine

Placebo Comparator group

Description:

continuous femoral nerve block with ropivacaine alone.

Treatment:

Drug: rocaine

rocaine with fentanyl

Active Comparator group

Description:

continuous femoral nerve block with combination of ropivacaine and fentanyl.

Treatment:

Drug: rocaine

Drug: Fentanyl