Analgesic Efficacy of Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

Tanta University

Status: Enrolling

Conditions: Multiple Mid-Transverse Process to Pleura; Idiopathic Scoliosis; PCA; Posterior Spinal Fusion

Treatments: Drug: Morphine; Other: Multiple Mid-Transverse Process to Pleura (MTP) Block

Study type: Interventional

Funder types: Other

Identifiers

NCT06820190

36264PR1047/1/25

Details and patient eligibility

About

This study aims to compare the analgesic efficacy of multiple mid-transverse process to pleura (MTP) block and PCA in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.

Full description

The postoperative period for idiopathic scoliosis patients undergoing posterior spinal fusion (PSF) is fraught with challenges, including adequate postoperative pain control and prolonged hospitalization.

Regional anesthesia techniques, mainly epidural analgesia and, more recently, paravertebral blocks, became crucial parts of the multimodal analgesia (MMA) regimen after introducing ultrasound (US) in the regional anesthesia practice. Erector spinae plane (ESP) block and mid-transverse to pleura (MTP) block are the latest developments in postoperative pain therapy.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Idiopathic scoliosis patients undergoing posterior spinal fusion surgery.

Exclusion criteria

• Patients with pre-existing infection at block site.
• Known allergy to study drugs.
• Coagulation disorder.
• History of psychiatric illness.
• Pre-existing neurological deficits.
• Patient with morbid obesity (body mass index >40 kg/m2).
• Presence of any pre-operative pain or history of chronic pain.
• History of regular analgesic.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

MTP group

Experimental group

Description:

Patients will receive multiple mid-transverse process to pleura (MTP) block after induction of anesthesia.

Treatment:

Other: Multiple Mid-Transverse Process to Pleura (MTP) Block

PCA group

Experimental group

Description:

Patients will receive IV-PCA. Morphine is generally administered as an initial loading dose of 0.05-0.1 mg/kg before the end of surgery, with PCA settings of a bolus dose of 0.01-0.03 mg/kg, a lockout interval of 6-10 min, and a background infusion of 0.01-0.02 mg/kg/h.

Treatment:

Drug: Morphine