Analgesic Efficacy of Quadratus Lumborum, Paravertebral Blocks

Gaziosmanpasa Research and Education Hospital

Status: Completed

Conditions: Postoperative Pain

Treatments: Procedure: Paravertebral Block; Procedure: Quadratus Lumborum Block II; Drug: Patient controlled intravenous analgesia; Procedure: Quadratus Lumborum Block III

Study type: Interventional

Funder types: Other

Identifiers

NCT05943015

GaziosmanpasaTREHEK

Details and patient eligibility

About

This trial is a prospective, randomized, single-center, single blinded-analysis trial, the objective of which is compare the postoperative analgesia efficacy of Quadratus lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy.

Full description

Laparoscopic approach in cholecystectomy surgery is frequently preferred because of its advantages in systemic complications, morbidity, mortality and hospital stay. Pain is one of the important causes of late discharge after surgery. Laparoscopic cholecystectomy surgery requires a multimodal analgesia approach because of its multiple pain components.Regional analgesia techniques are effective in reducing the side effects such as intraoperative opioid use, postoperative pain and nausea and vomiting. Quadratus lumborum block and paravertebral plane blocks are regional techniques performed for multimodal analgesia.

The aim of this study is to determine an effective analgesia method by comparing the postoperative analgesic effectiveness of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy surgery.

Enrollment: 122 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-65 years, American Society of Anesthesiologists physical statusⅠ-II

Exclusion criteria

• local anesthetic allergy
• Infection at the procedure site
• Body Mass Index >35 kg/m2
• Anticoagulant use with bleeding disorder
• Chronic analgesia and opioid use
• with mental and psychiatric disorders

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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122 participants in 3 patient groups

Quadratus Lumborum Block II

Active Comparator group

Description:

Quadratus Lumborum Block II

Treatment:

Drug: Patient controlled intravenous analgesia

Drug: Patient controlled intravenous analgesia

Procedure: Quadratus Lumborum Block II

Drug: Patient controlled intravenous analgesia

Quadratus Lumborum Block III

Active Comparator group

Description:

Quadratus Lumborum Block III

Treatment:

Drug: Patient controlled intravenous analgesia

Procedure: Quadratus Lumborum Block III

Drug: Patient controlled intravenous analgesia

Drug: Patient controlled intravenous analgesia

Paravertebral Block

Active Comparator group

Description:

Paravertebral Block

Treatment:

Drug: Patient controlled intravenous analgesia

Drug: Patient controlled intravenous analgesia

Drug: Patient controlled intravenous analgesia

Procedure: Paravertebral Block