Analgesic Mechanisms of Percutaneous Electrolysis

University of Salamanca

Status: Completed

Conditions: Pain Modulation; Endogenous Analgesia System; Analgesia; Pain; Percutaneous Electrolysis

Treatments: Other: Sham intervention; Other: Low intensity percutaneous electrolysis; Other: High intensity percutaneous electrolysis

Study type: Interventional

Funder types: Other

Identifiers

NCT05097937

EP550

Details and patient eligibility

About

Percutaneous electrolysis is based on the application of a galvanic current through an acupuncture needle. The underlying mechanisms that explain the efficacy of this technique are not completely well understood. The objective is to delve into the neurophysiological analgesic effects of percutaneous electrolysis. Participants will be assigned to one of three intervention groups. The analgesic effects of the technique will be evaluated by means of variables related to endogenous pain modulation.

Enrollment: 54 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Asymptomatic subjects
• Signature of the informed consent

Exclusion criteria

• Fear of needles
• Any pathology or process that causes pain
• Neurological, rheumatologic, cardiovascular or metabolic diseases
• Cutaneous alterations and cognitive or sensitivity disorders
• Pregnancy
• Recent intake of alcohol or caffeine
• Vigorous physical activity on the day of testing

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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54 participants in 3 patient groups

Sham intervention

Sham Comparator group

Description:

The needle will be inserted for 90 seconds without galvanic current.

Treatment:

Other: Sham intervention

Low intensity percutaneous electrolysis

Experimental group

Description:

Galvanic current will be applied with an intensity of 0.3 mA for 90 seconds.

Treatment:

Other: Low intensity percutaneous electrolysis

High intensity percutaneous electrolysis

Experimental group

Description:

Participants will receive three impacts of galvanic current with an intensity of 3 mA for 3 seconds each.

Treatment:

Other: High intensity percutaneous electrolysis